Strong painkillers from the opioid group act directly on the central nervous system, where they dampen pain processing. They are indispensable for severe acute pain, after surgery and in palliative medicine — but for chronic pain not related to cancer, their use is deliberately restricted and closely monitored. Careful management protects against tolerance and dependence.
Typical Areas of Use
- Severe pain after operations or injuries
- Cancer pain
- Severe pain conditions that do not respond to other medications
- Relief in palliative medicine
How It Works
- 1Your doctor will clarify the cause of the pain. For many common acute pains, as well as for longer-lasting pain without an underlying cancer condition, non-opioid medications and other measures are used first. In cases of severe acute pain, serious injuries, or after certain operations, however, opioids may be appropriate right from the start; separate treatment concepts apply for tumour-related and palliative pain.
- 2If an opioid is appropriate, the treatment goal and duration are clearly defined from the outset and possible risks are discussed openly.
- 3Treatment begins cautiously and is closely monitored: effectiveness, side effects and everyday functioning are assessed regularly.
- 4Once the goal is achieved or the medication no longer contributes to quality of life, it is reduced gradually under medical supervision.
How to Prepare
- Inform your doctor of any previous addiction disorders, including in the family.
- Mention sedatives and sleeping medications — the combination with opioids is particularly delicate.
- Clarify how the treatment will affect your ability to drive and your work.
Side Effects & Risks
- Common side effects include fatigue, nausea — especially at the start — and persistent constipation, which is usually addressed preventively.
- With prolonged use, the body develops tolerance; dependence is a real risk and the reason for close supervision.
- Your ability to react may be impaired — with consequences for driving and operating machinery.
- In case of overdose or when combined with alcohol and sedatives, opioids can dangerously suppress breathing.
- When stopping after prolonged use, withdrawal symptoms are possible — which is why the dose is reduced gradually.
Keep to the agreed follow-up appointments — they are an integral part of the treatment. Contact the practice if the effect diminishes, you feel the need for more, or if constipation becomes troublesome. Pronounced drowsiness, confusion or noticeably slow breathing are warning signs — in this situation, call the emergency number 144 immediately. Store the medication securely and out of children's reach, and never pass it on to others.

Cost & Insurance
Medically prescribed opioids are generally covered by basic health insurance — the deductible and co-payment apply as usual. Dispensing is strictly regulated by law and is done using a special controlled substance prescription. This is for guidance only without guarantee; in case of doubt, please contact your health insurance provider.
Frequently Asked Questions
- Do opioids inevitably lead to dependence?
- No — with short-term, targeted use under medical supervision, the risk is small. It increases with the duration of use and with certain risk factors. That is precisely why the goal and duration are defined from the outset and the course is closely monitored.
- Am I allowed to drive while taking opioids?
- During the adjustment phase and after dose changes, driving is not permitted. With stable, unchanged treatment, the ability to drive may be present — your doctor will assess this on a case-by-case basis. Never drive if you feel drowsy.
- Why am I being given an additional medication for constipation?
- Opioids slow down bowel activity, and this side effect persists — unlike nausea — usually throughout the entire treatment. Prevention is therefore more effective and more comfortable than treating severe constipation later.
- What happens if I stop the medication suddenly?
- After prolonged use, an abrupt stop can trigger withdrawal symptoms — such as restlessness, sweating, muscle aches and insomnia. Gradual reduction according to a medical plan largely avoids this.
- Are opioids useful for chronic back pain?
- Usually not: for chronic pain not related to cancer, the long-term benefit is often limited, but the risks are considerable. Movement therapy and multimodal pain treatment generally show better results in such cases.
